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自测试题

第二阶段测试题(免疫细胞)
最佳选择题( 2 0 × 5=100
1. T细胞的生物学功能不包括:
A. 产生细胞因子
B. 直接杀伤靶细胞
C. 参与对病毒的免疫应答
D. 诱导抗体的类别转换
E. 介导ADCC效应
2. 关于免疫细胞和膜分子,错误的组合是
A. 辅助性T细胞CD4抗原阳性
B. 单核吞噬细胞MHC-II类抗原阳性
C. 细胞毒性T细胞CD8抗原阳性
D. NK细胞-CD4抗原阳性
E. 人红细胞MHC-I类抗原阳性
3. B细胞表面最重要的标志为
A. SmIg
B. FcγR
C. CD40
D. CD5
E. CD80
4. Th1细胞分泌
A. IFN-γ
B. IL-4
C. IL-5
D. IL-6
E. IL-10
5. 有特异性抗原受体的细胞是
A. B淋巴细胞
B. 浆细胞
C. 巨噬细胞
D. NK细胞
E. 单核细胞
6. 可通过ADCC作用介导细胞毒作用的细胞是
A. 浆细胞
B. CTL
C. B细胞
D. NK细胞
E. 肥大细胞
7. 只有T细胞才具有的表面标记为
A. 识别抗原受体
B. C3受体
C. 细胞因子受体
D. CD3分子
E. 有丝分裂原受体
8. T细胞的表面分子
A. CD3
B. CD19
C. KIR
D. MHC-II
E. IL-2
9. 树突状细胞的表面分子
A. CD3
B. CD19
C. KIR
D. MHC-II
E. IL-2
10. NK细胞的表面分子
A. CD3
B. CD19
C. KIR
D. MHC-II
E. IL-2
11. What’s the most active and voracious white blood cell in the human body?
a. Platelet
b. Eosinophil
c. Macrophage
d. Neutrophil
e. Lymphocyte
12. Which of the following is NOT a function of the monocyte-macrophage cell line?
a. Ag presentation of T cells
b. Secretion of cytokines
c. Phagocytosis
d. Ag presentation to B cells
e. Immunoregulation
13. Which of the following is true of hematopoietic stem cells:
a. They are able to form all the cells in the blood
b. They cannot self renew
c. They produce only lymphocytes
d. They produce only granulocytes
e. None of the above
14. Which of the following types of antigens would not be recognized by T cells?
a. Polysaccharides
b. Proteins/peptides
c. Nucleic acids
d. a and c would not be recognized
e. None of them would be recognized
15. Which of the following is true about the thymus?
a. It is a primary lymphoid organ
b. It is the site of maturation of B cells
c. Cells which would react to ’self-Ag’ are eliminated during development in this organ
d. a and c
e. All of the above
16. Th1 cells do not
a. express CD4
b. produce IFN-γ
c. activate macrophages
d. bind soluble antigen
e. secrete IL-2
17. All of the following are true about receptors of the innate system, EXCEPT that they…
 a. include those of the toll family
  b. recognize molecular patterns associated with groups of microbes.
  c. include CD14 and scavenger receptors.
  d. include MHC molecules.
  e. do not include Igα and Igβ
18. Plasma cells are:
 a. T cells that have been triggered by antigen to mature to antibody-producing cells.
b. T cells that have migrated to germinal centers of the body.
 c. Cells that make plasma.
 d. B cells that have been stimulated by antigen to mature.
 e. none of the above.
19. B cells usually require T cell help to mature plasma cells because
a. T cells present antigen to them
b. most B cells in the circulation need thymic hormones secreted by the antigen presenting cell to mature to a plasma cell
c. T cells produce cytokines that enhance their responsiveness to antigen
d. all of the above
e. none of the above
20. Neutrophils are the primary cellular infiltrate in an antibody-mediated hypersensitivity because
a. they present antigen to T cells
b. they are capable of mediating ADCC
c. neutrophils respond to the chemotactic associated with complement activation
d. neutrophil diapedesis is difficult in the presence of chemotactic factors
e. none of the above


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