一、基本信息

周慧，女，1993年5月出生，医学博士，助理研究员，硕士生导师，扬州大学附属医院，邮箱：092762@yzu.edu.cn。

二、教育经历

2012.9—2016.7，山东第二医科大学，药学院，药学专业，学士

2016.9—2019.7，山东第二医科大学，药学院，微生物与生化药学专业，硕士

2019.9—2023.6，苏州大学，放射医学与防护学院，放射医学专业，博士

三、研究方向

主要从事分子影像探针的设计及其在疾病诊断、高效治疗等方面的应用基础研究。

四、承担项目

1. 国家自然科学基金青年基金项目“监测胰腺癌前病变的FN/LOX靶向分子探针的开发应用研究”3240100076，2025/01-2027/12，30万，主持；

2. 2025年江苏省青年科技人才托举工程，2025/01-2027/12，3万，主持；

3. 2024年度扬州市“绿扬金凤计划”卫生优秀博士资助项目，2025/01-2027/12，6万，主持；

4、扬州大学附属医院高层次人才引进科研启动项目，2023BS-ZH，20万，主持；

五、代表性论著

1. Zhou Hui, Zhang Yuan, Zhang Ruru, Zhao Min, Chen Wan, Liu Yinghua, Jiang Yue, Li Qing, Miao Qingqing^*, Gao Mingyuan^*. Atumor-microenvironment-activatable molecular pro-theranostic agent for photodynamic and immunotherapy of cancer[J].Advanced Materials, 2023, 35, e2211485.

2. Cai Wu^#, Fan Guohua^#,Zhou Hui^#, Chen Lei, Ge Jianxian, Huang Baoxing, Zhou Dandan, Zeng Jianfeng^*, Miao Qingqing^*, Hu Chunhong^*. Self-assembled hybrid nanocomposites for multimodal imaging-guided photothermal therapy of lymph node metastasis[J].ACS Applied Materials & Interfaces,2020, 12, 49407-49415.

3. Zhou Hui^#, Ge Jianxian^#, Miao Qingqing, Zhu Ran, Wen Ling, Zeng Jianfeng^*, Gao Mingyuan. Biodegradable inorganic nanoparticles for cancer theranostics: insights into the degradation behavior[J].Bioconjugate Chemistry,2020, 31, 315-331.

4. Zhou Hui, Tang Jinbao, Sun Lin, Zhang Jie, Chen Bochao, Kan Jianfei, Zhang Weifen, Zhang Jian, Zhou Jin^*. H₂S₂-triggered off-on fluorescent indicator with endoplasmic reticulum targeting for imaging in cells and zebrafishes[J].Sensors and Actuators B: Chemical,2019, 278, 64-72.

5. Zhou Hui^#, Tang Jinbao^#, Zhang Jie, Chen Bochao, Kan Jianfei, Zhang Weifen, Zhou Jin^*, Ma Huimin. A red lysosome-targeted fluorescent probe for carboxylesterase detection and bioimaging[J].Journal of Materials Chemistry B,2019, 7, 2989-2996.

6. Zhou Hui^#, Tang Jinbao^#, Lv Lulu, Sun Na, Zhang Jie, Chen Bochao, Mao Jing, Zhang Weifen, Zhang Jian，Zhou Jin^*.Intracellular endogenous glutathione detection and imaging by a simple and sensitive spectroscopic off-on probe[J].Analyst,2018, 143, 2390-2396.

7. Zhang Ruru, Chen Mei,Zhou Hui, Liu Yan, Wang Yi, Chen Can, Li Yueping,Zeng Jianfeng, Cui Jiabin^*, Duan Ruixue^*, Gao Mingyuan^*.Eliminating radioresistance with a magnetic ion-generator by simultaneously augmenting DNA damage and diminishing immunosuppression[J].Advanced Materials, 2025, 37, 2406378.

8. Zhao Min, Zhang Yuyang, Miao Jia,Zhou Hui, Jiang Yue, Zhang Yuan, Miao Minqian, Chen Wan, Xing Wei^*, Li Qing^*, Qingqing Miao^*.An activatable phototheranostic probe for anti-hypoxic typeI photodynamic- and immuno-therapy of cancer[J].Advanced Materials, 2023, 36, 2305243.

9. Zhou Jin^*,Zhou Hui, Tang Jinbao,Deng Shue,Yan Fang,Li Wenjing,Qu Meihua. Carbon dots doped with heteroatoms for fluorescent bioimaging:a review[J].Microchimica Acta,2017, 184, 343-368.

六、获奖情况

1. 2025年江苏省青年科技人才托举工程；

2. 2024年扬州市“绿扬金凤计划”优秀博士；