一、基本信息

刘婷婷，女，1989年10月出生，预防兽医学博士，助理研究员，硕士生导师，扬州大学附属医院，邮箱：apptx4869@126.com

二、教育经历

2009.9—2013.7，河南农业大学，牧医工程学院，动植物检疫专业，学士

2013.9—2019.7，华中农业大学，动物科学技术学院动物医学院学院，预防兽医学专业，博士

三、研究方向

主要从事溶瘤病毒3C蛋白诱导细胞凋亡的机制研究；以M13噬菌体为载体，研究其携带不同基因及相关靶向蛋白对肿瘤增殖的影响及在骨相关疾病的探究；

四、承担项目

江苏省青年基金项目“构建靶向和溶瘤双功能的M13噬菌体用于抗肿瘤的研究”批准号：BK20200950，2020-07至2023-06，20万元， 在研， 主持。

五、代表性论著

1、Liangliang Cai#;Tingting Liu#; Hujia Hua; Xingyu Jiang; Li Qian ; m6A modification patterns are associated with copy number burden and tumor immune landscape in thyroid cancer, BMC Endocrine Disorders, 2023, 23(1): 271.

2、Tingting Liu, Ningwei Zhao, mingze shi, Yuanzhao Shen, Chuanbin Mao, Xin Zhou.Phage-derived Oncolytic Viruses with 3C from Seneca Valley Virus for Targeted Therapy of Cervical Cancer. Advanced Therapeutics,2022, 5(8): 2200059.

3、Tingting Liu; Liangliang Cai; Hujia Hua; Xingyu Jiang; Xintian Xu; Tianyi Zhang; Wenqing Huang; Li Qian; Hua Bai; Jianchun Duan ; Cuprotosis Patterns Are Associated with Tumor Mutation Burden and Immune Landscape in Lung Adenocarcinoma., Journal of Oncology, 2022, 2022: 9772208.

4、Lin Cao#; Ran Zhang#;Tingting Liu#; Zixian Sun#; Mingxu Hu; Yuna Sun; Lingpeng Cheng; Yu Guo; Sheng Fu; Junjie Hu; Xiangmin Li; Chengqi Yu; Hanyang Wang; Huanchun Chen; Xueming Li; Elizabeth E. Fry; David I. Stuart*; Ping Qian*; Zhiyong Lou*; Zihe Rao; Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1, Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(51): 13087-13092.（共同第一作者）.

5、Liu, Tingting; Li, Xiangmin; Wu, Mengge; Qin, Liuxing; Chen, Huanchun; Qian, Ping*; Seneca Valley Virus 2C and 3C(pro) induce apoptosis via mitochondrion-mediated intrinsic pathway, Frontiers in Microbiology, 2019, 10: 1202-1202.

6、Wei Wen, Mengge Yin, Huawei Zhang, Tingting Liu, Huanchun Chen, Ping Qian, Junjie Hu, Xiangmin Li*;Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I. Virology,2019, 535: 122-129.

7、Qian Suhong#; Fan Wenchun#;Liu Tingting; Wu Mengge; Zhang Huawei; Cui Xiaofang; Zhou Yun; Hu Junjie; Wei Shaozhong; Chen Huanchun; Li Xiangmin*; Qian Ping*; Seneca Valley Virus suppresses host type I interferon production by targeting adaptor proteins MAVS, TRIF, and TANK for cleavage, Journal of Virology, 2017, 91(16): UNSP e00823-17.

8、Fan Wenchun;Liu Tingting; Li Xiangmin; Zhou Yun; Wu Mengge; Cui Xiaofang; Chen Huanchun; Qian Ping*; TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway, Molecular Immunology, 2017, 82: 114-1229.

六、获奖情况

2023年扬州市“绿扬金凤”计划优秀博士